Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852589 | 0.83 | LTA4H (0.64) | SMN1; SMN2LMNALTA4HHTTASAH1 | |
| SCHEMBL880293 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNALTA4HHTTCA1 | |
| SCHEMBL20221617 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNALTA4HHTTASAH1 | |
| SCHEMBL7134228 | 0.79 | TSHR (0.58) | SMN1; SMN2LMNAHTT | |
| SCHEMBL2607238 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNALTA4HHTTCA1 | |
| SCHEMBL8059055 | 0.77 | HTT (0.56) | SMN1; SMN2LMNALTA4HHTTMAPK1 | |
| SCHEMBL8760726 | 0.77 | TSHR (0.61) | SMN1; SMN2LMNAHTT | |
| SCHEMBL6239312 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNALTA4HHTTASAH1 | |
| SCHEMBL30473567 | 0.77 | L3MBTL1 (0.48) | SMN1; SMN2LMNALTA4HHTTASAH1 | |
| SCHEMBL24042644 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNALTA4HCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5772651-A | DEGASSED AQUEOUS SOLUTION; GASTROINTESTINAL SYSTEM | DIBRA S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |