Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | GGT1 | P19440 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445339 | 0.90 | BACE1 (0.40) | HTTTSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5094598 | 0.89 | HTT (0.37) | HTTTSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8724020 | 0.79 | MAPT (0.41) | TSHRKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7888138 | 0.79 | HTT (0.36) | HTTTSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7128812 | 0.78 | MAPT (0.40) | HTTKDM4EALDH1A1TDP1MAPT | |
| SCHEMBL7120307 | 0.76 | HIF1A (0.36) | HTTALDH1A1HPGDPTPN1LMNA | |
| SCHEMBL7553115 | 0.75 | PDE4D (0.39) | HTTTSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL13219265 | 0.73 | CNR1 (0.32) | — | |
| SCHEMBL8782636 | 0.73 | GPR84 (0.39) | KDM4EALDH1A1HPGDPTGS1PTGS2 | |
| SCHEMBL1387363 | 0.72 | BCHE (0.35) | HTTKDM4EALDH1A1PTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744070-A | Photochromic substituted naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1998-04-28 | — | — | US | claimed |
| US-5744070-A | Photochromic substituted naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1998-04-28 | — | — | US | disclosed |