Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CD74 | P04233 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445339 | 0.88 | BACE1 (0.40) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8722690 | 0.79 | HTT (0.43) | MAPTTDP1NPC1RAB9AKDM4E | |
| SCHEMBL7553115 | 0.76 | PDE4D (0.39) | MAPTTDP1KDM4EALDH1A1KMT2A | |
| SCHEMBL8782636 | 0.73 | GPR84 (0.39) | MAPTTDP1CASP3SENP7NPC1 | |
| SCHEMBL9257841 | 0.72 | KDM4E (0.41) | MAPTTDP1NPC1KDM4EALDH1A1 | |
| SCHEMBL5094598 | 0.72 | HTT (0.37) | MAPTTDP1KDM4EALDH1A1KMT2A | |
| SCHEMBL8727667 | 0.72 | GABRA1 (0.34) | MAPTTDP1NPC1RAB9AKDM4E | |
| SCHEMBL8311131 | 0.71 | EP300 (0.35) | MAPTCASP3SENP7NPC1RAB9A | |
| SCHEMBL5615531 | 0.71 | ALDH1A1 (0.43) | MAPTTDP1NPC1RAB9AKDM4E | |
| SCHEMBL5615321 | 0.69 | SMN1; SMN2 (0.43) | MAPTTDP1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744070-A | Photochromic substituted naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1998-04-28 | — | — | US | claimed |
| US-5744070-A | Photochromic substituted naphthopyran compounds | TRANSITIONS OPTICAL, INC. (US) | 1998-04-28 | — | — | US | disclosed |