Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 8/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8754565 | 0.93 | CHKA (0.37) | CHKACSNK2A2CSNK2BCSNK2A1MEN1 | |
| Iodide SCHEMBL2551843 | 0.91 | CHKA (0.36) | CHKACSNK2A2CSNK2BCSNK2A1MEN1 | |
| Trifluoroacetic Acid SCHEMBL14672349 | 0.82 | PDK1 (0.36) | TP53ALDH1A1 | |
| SCHEMBL4624927 | 0.79 | CHKA (0.40) | CHKACHKB | |
| SCHEMBL8725231 | 0.79 | RAB9A (0.49) | — | |
| SCHEMBL5892434 | 0.77 | POLB (0.38) | CHKACSNK2A2CSNK2BCSNK2A1TP53 | |
| Iodide SCHEMBL5892308 | 0.75 | POLB (0.37) | CHKACSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL4523362 | 0.71 | CSNK2A2 (0.36) | CHKACSNK2A2CSNK2BCSNK2A1TP53 | |
| SCHEMBL6334519 | 0.70 | RAB9A (0.50) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6341143 | 0.68 | RAB9A (0.49) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643698-B1 | SPECTROPHOTOMETRIC METHODS FOR ASSAYING TOTAL MERCAPTANS, REDUCED GLUTATHIONE (GSH) AND MERCAPTANS OTHER THAN GSH IN AN AQUEOUS MEDIUM, REAGENTS AND KITS FOR THEIR IMPLEMENTATION | OXIS INT SA (FR) | 1997-03-05 | — | — | EP | claimed |
| US-5817520-A | USING A QUINOLINIUM INDICATOR | OXIS INTERNATIONAL S.A. (FR) | 1998-10-06 | — | — | US | disclosed |