SCHEMBL8725231

SCHEMBL8725231

C[n+]1ccc(Cl)c2ccccc21.F[B-](F)(F)F

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.49
RCE1 Q9Y256 1/20 0.49
ACHE P22303 7/20 0.46
CHAT P28329 1/20 0.44
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
MAPK1 P28482 1/20 0.41
HTT P42858 1/20 0.41
RAD52 P43351 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6334519 0.92 RAB9A (0.50) RAB9ARCE1ACHECHATMAPT
Iodide SCHEMBL10546532 0.90 RAB9A (0.49) RAB9ARCE1ACHECHATMAPT
Hydrochloric Acid SCHEMBL6341143 0.90 RAB9A (0.49) RAB9ARCE1ACHECHATMAPT
SCHEMBL6338379 0.79 RAB9A (0.50) RAB9ARCE1ACHECHATMAPT
SCHEMBL8722744 0.79 CHKA (0.34)
SCHEMBL4625719 0.77 KDM4E (0.41) RAB9AACHEMAPTPKMMAPK1
SCHEMBL6745095 0.75 RAB9A (0.46) RAB9ARCE1ACHECHATMAPT
SCHEMBL7918806 0.74 CHAT (0.55) RAB9ARCE1ACHECHATMAPT
SCHEMBL3323373 0.74 LMNA (0.40) RAB9ARCE1CHATPKMMAPK1
SCHEMBL8722519 0.74 ACHE (0.39) ACHEMAPTHTTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0643698-B1 SPECTROPHOTOMETRIC METHODS FOR ASSAYING TOTAL MERCAPTANS, REDUCED GLUTATHIONE (GSH) AND MERCAPTANS OTHER THAN GSH IN AN AQUEOUS MEDIUM, REAGENTS AND KITS FOR THEIR IMPLEMENTATION OXIS INT SA (FR) 1997-03-05 EP claimed
US-5817520-A USING A QUINOLINIUM INDICATOR OXIS INTERNATIONAL S.A. (FR) 1998-10-06 US disclosed