Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | RAD52 | P43351 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 5/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4581596 | 0.86 | SLC6A9 (0.39) | MAPTRAD52LMNAALDH1A1GFER | |
| SCHEMBL8723002 | 0.85 | SLC6A9 (0.38) | MAPTRAD52LMNAALDH1A1GFER | |
| SCHEMBL8722452 | 0.84 | MAPT (0.37) | MAPTRAD52LMNAALDH1A1GFER | |
| SCHEMBL8722456 | 0.83 | RAD52 (0.37) | MAPTRAD52LMNAALDH1A1GFER | |
| Hydrochloric Acid SCHEMBL8719317 | 0.82 | RAD52 (0.36) | MAPTRAD52LMNAALDH1A1GFER | |
| SCHEMBL6320212 | 0.79 | LMNA (0.44) | MAPTRAD52LMNAALDH1A1GFER | |
| SCHEMBL8723022 | 0.74 | CASP6 (0.33) | MAPTALDH1A1GFERCASP6KDM4E | |
| SCHEMBL8930521 | 0.73 | GFER (0.36) | MAPTALDH1A1GFERCASP6TP53 | |
| Hydrochloric Acid SCHEMBL8722394 | 0.71 | SLC6A9 (0.30) | — | |
| SCHEMBL4581605 | 0.71 | MAPT (0.42) | MAPTLMNAALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0814849-A1 | MAGNETICALLY LABELED CHEMOATTRACTANTS AS TARGETED CONTRAST AGENTS IN THE NMR IMAGING OF LIVING TISSUES | BRACCO International B.V. (NL) | 1998-01-07 | — | — | EP | disclosed |
| WO-1997014443-A1 | MAGNETICALLY LABELED CHEMOATTRACTANTS AS TARGETED CONTRAST AGENTS IN THE NMR IMAGING OF LIVING TISSUES | BRACCO INTERNATIONAL B.V. (NL) | 1997-04-24 | — | — | WO | disclosed |