Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872342 | 0.98 | DPP4 (0.61) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL7447078 | 0.95 | DPP4 (0.57) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL497605 | 0.91 | MAOA (0.60) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL497847 | 0.83 | DPP4 (0.59) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL3890243 | 0.77 | DPP4 (0.63) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL6409381 | 0.77 | DPP4 (0.63) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL19382461 | 0.77 | DPP4 (0.63) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL8122483 | 0.77 | DPP4 (0.63) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL294582 | 0.77 | DPP4 (1.00) | DPP4SLC6A4SLC6A2SLC6A3MAOA | |
| SCHEMBL1152119 | 0.77 | DPP4 (0.63) | DPP4SLC6A4SLC6A2SLC6A3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2157084-B1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVE | KOWA CO (JP) | 2013-05-22 | — | — | EP | disclosed |
| US-8106053-B2 | 5-phenyl-3-pyridazinone derivative | KOWA COMPANY, LTD. | 2012-01-31 | — | — | US | disclosed |
| US-20100197698-A1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVE | KOWA COMPANY, LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
| EP-2157084-A1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVE | Kowa Company, Ltd. (JP) | 2010-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197698-A1 | 5-PHENYL-3-PYRIDAZINONE DERIVATIVE | SERPINE1, MMP1, PLAT | DPP4 192/4885SLC6A4 3564/4885SLC6A2 4213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.