Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.44 |
| ▸ | ADH1B | P00325 | 1/20 | 0.43 |
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH1A | P07327 | 1/20 | 0.43 |
| ▸ | ADH7 | P40394 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14304765 | 0.79 | LMNA (0.45) | MEN1KMT2AHTTKCNA5MAPT | |
| SCHEMBL8721549 | 0.79 | MEN1 (0.50) | MEN1KMT2AHTTMAPTLMNA | |
| SCHEMBL15256260 | 0.76 | MEN1 (0.47) | MEN1KMT2AHTTMAPTLMNA | |
| SCHEMBL6687981 | 0.76 | MEN1 (0.55) | MEN1KMT2AHTTMAPTLMNA | |
| SCHEMBL28365055 | 0.76 | MEN1 (0.55) | MEN1KMT2AHTTMAPTLMNA | |
| SCHEMBL27522015 | 0.76 | MEN1 (0.55) | MEN1KMT2AHTTMAPTLMNA | |
| SCHEMBL1377592 | 0.76 | KMT2A (0.55) | MEN1KMT2AHTTMAPTLMNA | |
| SCHEMBL27880788 | 0.76 | KMT2A (0.55) | MEN1KMT2AHTTMAPTLMNA | |
| SCHEMBL27587586 | 0.75 | HPGD (0.51) | MEN1KMT2AHTTKCNA5MAPT | |
| SCHEMBL14303134 | 0.74 | ALDH1A1 (0.48) | MEN1KMT2AHTTKCNA5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830915-A | ORAL DISEASES; SKIN DISORDERS; ANTIINFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1998-11-03 | — | — | US | claimed |
| WO-2008003809-A1 | ANTITUMOUR COMPOUNDS | PHARMA MAR, S.A. (ES) | 2008-01-10 | — | — | WO | disclosed |
| US-5830915-A | ORAL DISEASES; SKIN DISORDERS; ANTIINFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1998-11-03 | — | — | US | disclosed |