⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5874277 | 0.81 | KMT2A (0.30) | — | |
| SCHEMBL5874405 | 0.81 | TSHR (0.32) | — | |
| SCHEMBL1845257 | 0.77 | TSHR (0.33) | — | |
| SCHEMBL4661613 | 0.77 | ELANE (0.35) | — | |
| SCHEMBL5875252 | 0.77 | TSHR (0.32) | — | |
| SCHEMBL5875270 | 0.77 | TSHR (0.37) | — | |
| SCHEMBL5875417 | 0.76 | LMNA (0.35) | — | |
| SCHEMBL5874610 | 0.74 | ALDH1A1 (0.44) | — | |
| SCHEMBL8968148 | 0.72 | HTT (0.34) | — | |
| SCHEMBL5875157 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643068-B1 | ERYTHROMYCIN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1998-08-19 | — | — | EP | disclosed |
| US-5658888-A | ENTEROKINESIS STIMULATING ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0643068-A1 | ERYTHROMYCIN DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0392745-B1 | Immunoconjugates and prodrugs and their use in association for drug delivery | CELLTECH LTD (GB) | 1994-11-02 | — | — | EP | disclosed |
| EP-0392745-A2 | Immunoconjugates and prodrugs and their use in association for drug delivery | CELLTECH LIMITED (GB) | 1990-10-17 | — | — | EP | disclosed |