Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721644 | 0.86 | PIM1 (0.34) | MAPTGAAMEN1KMT2AST14 | |
| SCHEMBL8723581 | 0.81 | ST14 (0.42) | LMNAMAPTGAAMEN1KMT2A | |
| SCHEMBL7848802 | 0.81 | KDM4E (0.51) | LMNAMAPTALDH1A1MT-CO2SMN1; SMN2 | |
| SCHEMBL8721599 | 0.78 | MAPT (0.40) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL8727224 | 0.76 | ALDH1A1 (0.35) | LMNAMAPTGAAMEN1KMT2A | |
| SCHEMBL8721632 | 0.75 | F2 (0.44) | KMT2AST14F2 | |
| SCHEMBL8722523 | 0.75 | TSHR (0.40) | ALDH1A1MAPK1SIRT2 | |
| SCHEMBL17198821 | 0.74 | NPC1 (0.55) | LMNAGAAALDH1A1ST14IDO1 | |
| SCHEMBL6682075 | 0.74 | ST14 (0.45) | LMNAGAAKMT2AST14IDO1 | |
| [11C]Phenethylguanidine SCHEMBL837644 | 0.74 | NPC1 (0.59) | LMNAMAPTGAAALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040705-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR (US) | 1996-12-19 | — | — | WO | disclosed |