Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 6/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682075 | 0.87 | ST14 (0.45) | ST14LMNAGAAKMT2AIDO1 | |
| SCHEMBL8721646 | 0.84 | PIM1 (0.35) | ST14ALDH1A1MAPTMEN1GAA | |
| SCHEMBL8723577 | 0.81 | LMNA (0.39) | ST14ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL26005420 | 0.77 | ST14 (0.46) | ST14ALDH1A1MAPTLMNAGAA | |
| SCHEMBL12401907 | 0.76 | ST14 (0.51) | ST14LMNAMEN1GAAKMT2A | |
| SCHEMBL8721602 | 0.74 | MAPT (0.41) | ST14ALDH1A1MAPTMEN1GAA | |
| SCHEMBL6682640 | 0.74 | ST14 (0.50) | ST14LMNAGAAKMT2AIDO1 | |
| SCHEMBL1286912 | 0.74 | KDM4E (0.56) | ST14ALDH1A1MAPTGAAKMT2A | |
| SCHEMBL6679010 | 0.74 | ST14 (0.50) | ST14ALDH1A1IDO1CA1CA2 | |
| SCHEMBL23135379 | 0.74 | ADRA2A (0.45) | ST14ALDH1A1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040705-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR (US) | 1996-12-19 | — | — | WO | disclosed |