Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28285324 | 0.84 | CA12 (0.42) | KDM4EMAPTALDH1A1GAAEGFR | |
| SCHEMBL8723668 | 0.79 | MAPK10 (0.38) | NPC1RAB9AMAPTALDH1A1EGFR | |
| SCHEMBL13352440 | 0.73 | KDM4E (0.52) | CDC7TBXA2RKDM4ETP53DHODH | |
| SCHEMBL16481157 | 0.71 | CDC7 (0.71) | CDC7KDM4ETP53MAPTALDH1A1 | |
| SCHEMBL8725399 | 0.71 | EGFR (0.44) | KDM4ENPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL27374955 | 0.69 | CDC7 (0.49) | CDC7TBXA2RDHODHNPC1RAB9A | |
| SCHEMBL30751294 | 0.69 | CDC7 (0.49) | CDC7TBXA2RDHODHNPC1RAB9A | |
| SCHEMBL184366 | 0.69 | — | — | |
| SCHEMBL8169486 | 0.69 | PRSS1 (0.39) | ALDH1A1 | |
| SCHEMBL3932390 | 0.68 | NPC1 (0.41) | KDM4EDHODHNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040705-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR (US) | 1996-12-19 | — | — | WO | disclosed |