Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721645 | 0.88 | MAPT (0.55) | MAPK1MAPTKDM4EL3MBTL1NPC1 | |
| SCHEMBL28318419 | 0.83 | GAA (0.50) | EGFRMAPK1MAPTKDM4EL3MBTL1 | |
| SCHEMBL8723668 | 0.79 | MAPK10 (0.38) | EGFRMAPK1MAPTNPC1RAB9A | |
| SCHEMBL8721665 | 0.75 | GAA (0.38) | EGFRMAPK1MAPTKDM4EL3MBTL1 | |
| SCHEMBL4838147 | 0.73 | CA1 (0.35) | MAPK1MAPTKDM4EL3MBTL1NPC1 | |
| SCHEMBL866356 | 0.73 | MAPT (0.77) | EGFRERBB3MAOBMAOAMAPK1 | |
| SCHEMBL7844969 | 0.73 | MTNR1B (0.64) | MAOBMAPK1MAPTKDM4EL3MBTL1 | |
| SCHEMBL8327622 | 0.71 | MAOB (0.43) | MAOBMAPTKDM4EL3MBTL1NPC1 | |
| SCHEMBL8723610 | 0.71 | CDC7 (0.45) | EGFRMAPTKDM4ENPC1GAA | |
| SCHEMBL4242 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040705-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR (US) | 1996-12-19 | — | — | WO | disclosed |