Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982320 | 0.86 | MAPT (0.41) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL27911517 | 0.84 | SOS1 (0.41) | SOS1 | |
| SCHEMBL8721665 | 0.83 | GAA (0.38) | MAPK10MAPTMEN1KMT2APRKD3 | |
| SCHEMBL29072561 | 0.83 | SOS1 (0.44) | MAPTMEN1KMT2ASOS1RAB9A | |
| SCHEMBL8721689 | 0.83 | NTRK1 (0.38) | MEN1KMT2ARAB9ANPC1KCNH3 | |
| SCHEMBL29072539 | 0.83 | MEN1 (0.41) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL29072550 | 0.81 | RAPGEF4 (0.46) | MAPK10MEN1KMT2AEGFRALDH1A1 | |
| SCHEMBL29072563 | 0.79 | KMT2A (0.43) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8723610 | 0.79 | CDC7 (0.45) | MAPK10MAPTMEN1KMT2APRKD3 | |
| SCHEMBL8725399 | 0.79 | EGFR (0.44) | MAPTMEN1KMT2AEGFRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040705-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR (US) | 1996-12-19 | — | — | WO | disclosed |