SCHEMBL8723710

SCHEMBL8723710

CC1CCCN(NC(=S)S)C1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.38
RAB9A P51151 3/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 4/20 0.37
GAA P10253 2/20 0.36
MAPT P10636 3/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.35
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
HPGD P15428 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8723713 0.79 GAA (0.38) ALDH1A1RAB9ANPC1POLBGAA
SCHEMBL8718774 0.76 PHGDH (0.42) ALDH1A1RAB9ANPC1POLBMAPT
Selenium SCHEMBL30199362 0.75 PHGDH (0.41) ALDH1A1RAB9ANPC1POLBMAPT
SCHEMBL5009125 0.74 KDM4E (0.37) ALDH1A1RAB9APOLBGAAMAPT
SCHEMBL221278 0.73
SCHEMBL31283176 0.73 ALDH1A1 (0.46) ALDH1A1MAPTLMNAKDM4ESMN1; SMN2
SCHEMBL7512448 0.72 KMT2A (0.48) ALDH1A1RAB9ANPC1POLBGAA
SCHEMBL23581934 0.71 ALDH1A1 (0.40) ALDH1A1RAB9ANPC1POLBMAPT
SCHEMBL19243862 0.71
Potassium SCHEMBL7562143 0.71 ALDH1A1 (0.43) ALDH1A1MAPTLMNAKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5789138-A Optical recording medium and method of producing the same RICOH COMPANY, LTD. (JP) 1998-08-04 US disclosed