SCHEMBL8723713

SCHEMBL8723713

CC1CCCN(NC(O)=S)C1.NC(O)=S

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.38
ALDH1A1 P00352 7/20 0.37
RAB9A P51151 2/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
NPC1 O15118 1/20 0.36
POLB P06746 2/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8723710 0.79 ALDH1A1 (0.38) GAAALDH1A1RAB9AMAPTMEN1
SCHEMBL5009125 0.79 KDM4E (0.37) GAAALDH1A1RAB9AMAPTMEN1
SCHEMBL8718776 0.78 PHGDH (0.39) GAAALDH1A1RAB9AMAPTNPC1
SCHEMBL3066005 0.75 HTT (0.35) ALDH1A1MAPTKDM4ECA12CA1
SCHEMBL7758216 0.73 HTT (0.34) CA12CA1CA2CA9
SCHEMBL3074878 0.73 HTT (0.38) ALDH1A1MEN1KMT2AL3MBTL1CA12
Ammonia Solution, Strong SCHEMBL28405557 0.73 HTT (0.34) ALDH1A1MAPTLMNACA12CA1
SCHEMBL6515029 0.71 HTT (0.37) ALDH1A1CA12CA1CA2CA9
SCHEMBL6040359 0.70 MGLL (0.37) ALDH1A1POLBLMNA
SCHEMBL7512448 0.69 KMT2A (0.48) GAAALDH1A1RAB9AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5789138-A Optical recording medium and method of producing the same RICOH COMPANY, LTD. (JP) 1998-08-04 US disclosed