Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512945 | 0.82 | KMT2A (0.45) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL7509993 | 0.80 | ALDH1A1 (0.55) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL7515932 | 0.72 | KMT2A (0.53) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL8723710 | 0.72 | ALDH1A1 (0.38) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL7537718 | 0.71 | GNAI3 (0.54) | KMT2AMEN1MAPTPOLB | |
| SCHEMBL8585263 | 0.71 | GNAI3 (0.47) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL7507205 | 0.71 | LMNA (0.53) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL6582896 | 0.70 | MAPT (0.47) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL8723713 | 0.69 | GAA (0.38) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL17219 | 0.66 | KMT2A (0.57) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876300-B1 | USE OF THIOUREA COMPOUNDS FOR CONTROLLING BIOFOULING | BUCKMAN LABOR INC (US) | 2002-01-02 | — | — | EP | claimed |
| US-6075022-A | Methods and compositions for controlling biofouling using thiourea compounds | BUCKMAN LABORATORIES INTERNATIONAL INC. (US) | 2000-06-13 | — | — | US | claimed |
| EP-0876300-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING THIOUREA COMPOUNDS | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1998-11-11 | — | — | EP | claimed |
| WO-1997011911-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING THIOUREA COMPOUNDS | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1997-04-03 | — | — | WO | claimed |
| EP-0876300-B1 | USE OF THIOUREA COMPOUNDS FOR CONTROLLING BIOFOULING | BUCKMAN LABOR INC (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6075022-A | Methods and compositions for controlling biofouling using thiourea compounds | BUCKMAN LABORATORIES INTERNATIONAL INC. (US) | 2000-06-13 | — | — | US | disclosed |
| EP-0876300-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING THIOUREA COMPOUNDS | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997011911-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING THIOUREA COMPOUNDS | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1997-04-03 | — | — | WO | disclosed |