Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8723797 | 1.00 | CES2 (0.31) | CES2BCHECES1 | |
| SCHEMBL20356016 | 0.78 | CES2 (0.39) | CES2BCHECES1 | |
| SCHEMBL20356019 | 0.77 | CES2 (0.39) | CES2BCHECES1 | |
| SCHEMBL24536159 | 0.73 | ALDH1A1 (0.59) | — | |
| SCHEMBL24536156 | 0.73 | IDO1 (0.46) | CES2BCHECES1 | |
| SCHEMBL7295982 | 0.73 | CES2 (0.35) | CES2BCHECES1 | |
| SCHEMBL942875 | 0.72 | — | — | |
| SCHEMBL2811679 | 0.68 | — | — | |
| SCHEMBL5249073 | 0.68 | NOS2 (0.33) | — | |
| SCHEMBL30257704 | 0.68 | HPRT1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609058-B1 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |