Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22585911 | 0.90 | ALDH1A1 (0.37) | NOTUMSMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL4878975 | 0.85 | NOTUM (0.44) | NOTUMSMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL5500501 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1RAB9AKMT2AADORA2A | |
| SCHEMBL12068347 | 0.82 | GSK3B (0.49) | SMN1; SMN2MEN1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL25610999 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1RAB9AKMT2AADORA2A | |
| SCHEMBL1917870 | 0.82 | ADORA3 (0.50) | SMN1; SMN2MEN1RAB9AKMT2AADORA2A | |
| SCHEMBL14895111 | 0.82 | LOXL2 (0.47) | NOTUMSMN1; SMN2MEN1RAB9AKMT2A | |
| SCHEMBL28401740 | 0.81 | CHRM1 (0.49) | TDP1MEN1KMT2ACYP3A4KDM4E | |
| SCHEMBL11097956 | 0.79 | SSTR1 (0.43) | SMN1; SMN2MEN1RAB9AKMT2AADORA2A | |
| SCHEMBL6618330 | 0.79 | GSK3B (0.44) | SMN1; SMN2RAB9AADORA2AADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876370-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997025325-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-17 | — | — | WO | disclosed |