SCHEMBL8724008

SCHEMBL8724008

C=CCc1ccc2ccc3ccc4ccc5cccc6c1c2c3c4c56

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.43
HPGD P15428 4/20 0.43
CYP1A2 P05177 3/20 0.43
HSD17B10 Q99714 3/20 0.43
THRB P10828 2/20 0.43
GABRA1 P14867 2/20 0.39
GABRB2 P47870 2/20 0.39
ERBB2 P04626 1/20 0.36
FYN P06241 1/20 0.36
MAOA P21397 1/20 0.36
ACHE P22303 1/20 0.36
AHR P35869 1/20 0.36
KMT2A Q03164 5/20 0.36
MEN1 O00255 4/20 0.36
CYP3A4 P08684 2/20 0.36
TSHR P16473 2/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
KDM4E B2RXH2 3/20 0.35
MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL729571 0.95 ALDH1A1 (0.47) ALDH1A1HPGDCYP1A2HSD17B10THRB
SCHEMBL27930641 0.93 ALDH1A1 (0.55) ALDH1A1HPGDCYP1A2HSD17B10THRB
Acetic Acid SCHEMBL27947444 0.83 ALDH1A1 (0.44) ALDH1A1HPGDCYP1A2HSD17B10THRB
SCHEMBL728402 0.83 KMT2A (0.47) ALDH1A1HPGDCYP1A2HSD17B10THRB
SCHEMBL12827498 0.82 GABRA1 (0.42) ALDH1A1HPGDCYP1A2HSD17B10THRB
SCHEMBL16487070 0.81 ALDH1A1 (0.43) ALDH1A1HPGDCYP1A2HSD17B10THRB
SCHEMBL8724012 0.81 CYP1A2 (0.49) ALDH1A1HPGDCYP1A2HSD17B10THRB
SCHEMBL5831194 0.80 GABRA1 (0.52) ALDH1A1HPGDCYP1A2HSD17B10THRB
SCHEMBL28831011 0.79 ALDH1A1 (0.45) ALDH1A1HPGDCYP1A2HSD17B10THRB
SCHEMBL7749583 0.78 GABRA1 (0.41) ALDH1A1HPGDCYP1A2HSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0539967-B1 Sensors and methods for sensing MINNESOTA MINING & MFG (US) 1998-09-09 EP disclosed
US-5498549-A A FLUORESCENT POLYNUCLEAR COMPOUND COVALENTLY BONDED TO A POLYSILOXANE MATRIX, BLOOD GASES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-03-12 US disclosed
US-5409666-A Quantitative analysis MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-25 US disclosed
EP-0539967-A1 Sensors and methods for sensing MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-05-05 EP disclosed
EP-0528081-A1 Gas sensor and methods for making and using same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-02-24 EP disclosed