SCHEMBL8724012

SCHEMBL8724012

C=CCc1cc2ccc3cccc4c5cccc6ccc1c(c65)c2c34

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.49
ERBB2 P04626 1/20 0.49
FYN P06241 1/20 0.49
MAOA P21397 1/20 0.49
ACHE P22303 1/20 0.49
AHR P35869 1/20 0.49
ALDH1A1 P00352 5/20 0.44
HPGD P15428 3/20 0.44
HSD17B10 Q99714 3/20 0.44
THRB P10828 1/20 0.44
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GABRA1 P14867 2/20 0.36
GABRB2 P47870 2/20 0.36
CYP3A4 P08684 2/20 0.35
TSHR P16473 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KDM4E B2RXH2 2/20 0.35
AURKA O14965 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728402 0.82 KMT2A (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4488247 0.82 CYP1A2 (0.43) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL27930641 0.81 ALDH1A1 (0.55) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL8724008 0.81 ALDH1A1 (0.43) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL1685061 0.81 GABRA1 (0.45) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL729571 0.79 ALDH1A1 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL25430146 0.79 SRD5A1 (0.37) CYP1A2GABRA1GABRB2CYP3A4SRD5A1
SCHEMBL25430661 0.78 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL28831011 0.78 ALDH1A1 (0.45) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL4338851 0.78 MEN1 (0.37) CYP1A2ALDH1A1HPGDHSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0539967-B1 Sensors and methods for sensing MINNESOTA MINING & MFG (US) 1998-09-09 EP disclosed
US-5498549-A A FLUORESCENT POLYNUCLEAR COMPOUND COVALENTLY BONDED TO A POLYSILOXANE MATRIX, BLOOD GASES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-03-12 US disclosed
US-5409666-A Quantitative analysis MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-25 US disclosed
EP-0539967-A1 Sensors and methods for sensing MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-05-05 EP disclosed
EP-0528081-A1 Gas sensor and methods for making and using same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-02-24 EP disclosed