Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 5/20 | 0.37 |
| ▸ | GABRD | O14764 | 5/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.37 |
| ▸ | GABRE | P78334 | 5/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27789467 | 0.83 | GABRP (0.43) | CASP6G6PDCASP7GABRPGABRD | |
| SCHEMBL10626499 | 0.81 | CASP6 (0.39) | CASP6G6PDCASP7GABRPGABRD | |
| SCHEMBL9017949 | 0.81 | CYP1A2 (0.35) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27789457 | 0.80 | GABRP (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7160625 | 0.79 | KDM4E (0.41) | CASP6G6PDCASP7GABRPGABRD | |
| SCHEMBL626005 | 0.78 | DHODH (0.38) | CASP6G6PDCASP7GABRPGABRD | |
| Hydrochloric Acid SCHEMBL9258689 | 0.78 | GABRP (0.42) | CASP6G6PDCASP7GABRPGABRD | |
| SCHEMBL27799042 | 0.78 | PPARA (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10435402 | 0.78 | PPARA (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7720169 | 0.77 | G6PD (0.56) | CASP6G6PDCASP7ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716990-A | PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1998-02-10 | — | — | US | disclosed |
| EP-0408546-B1 | IMPROVEMENTS RELATING TO DRUG DELIVERY SYSTEMS | CANCER RES CAMPAIGN TECH (GB) | 1994-04-27 | — | — | EP | disclosed |
| EP-0408546-A1 | IMPROVEMENTS RELATING TO DRUG DELIVERY SYSTEMS. | CANCER RES CAMPAIGN TECH (GB) | 1991-01-23 | — | — | EP | disclosed |
| WO-1988007378-A1 | IMPROVEMENTS RELATING TO DRUG DELIVERY SYSTEMS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LTD. (GB) | 1988-10-06 | — | — | WO | disclosed |