Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7171950 | 0.89 | MAPK1 (0.41) | MAPK1KMT2AHPGDTSHRALDH1A1 | |
| SCHEMBL7171946 | 0.89 | MAPK1 (0.41) | MAPK1KMT2AHPGDTSHRALDH1A1 | |
| SCHEMBL8724339 | 0.88 | GABRA5 (0.40) | MAPK1KMT2AGABRA5HPGDTP53 | |
| SCHEMBL2851880 | 0.83 | GABRA5 (0.42) | MAPK1KMT2AGABRA5TP53HTT | |
| SCHEMBL20636585 | 0.83 | HTR7 (0.38) | MAPK1KMT2ATP53HTTFOLH1 | |
| SCHEMBL2851872 | 0.83 | GABRA5 (0.42) | MAPK1KMT2AGABRA5TP53HTT | |
| SCHEMBL8338895 | 0.83 | GABRA5 (0.42) | MAPK1KMT2AGABRA5TP53HTT | |
| SCHEMBL28357488 | 0.83 | BCL2 (0.35) | TP53HTTFOLH1CYP2C19 | |
| SCHEMBL8639304 | 0.83 | KDM4E (0.47) | TP53HTTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL6415157 | 0.82 | TDP1 (0.39) | KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840726-A1 | PROCESS FOR THE PREPARATION OF 2-(6-SUBSTITUTED PYRID-2-YLOXYMETHYL)PHENYLACETATE | ZENECA LIMITED (GB) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997001538-A1 | PROCESS FOR THE PREPARATION OF 2-(6-SUBSTITUTED PYRID-2-YLOXYMETHYL)PHENYLACETATE | ZENECA LIMITED (GB) | 1997-01-16 | — | — | WO | disclosed |