Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.36 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729280 | 0.94 | TNFRSF1A (0.41) | POLBHDAC6SMPD1TNFRSF1AMAPT | |
| SCHEMBL8723328 | 0.91 | MAPT (0.43) | HDAC6SMPD1MAPTCYP3A4CYP1A2 | |
| SCHEMBL8075506 | 0.90 | CSF1R (0.39) | SMPD1MAPTCYP3A4CYP1A2CYP2C9 | |
| SCHEMBL8080467 | 0.88 | THRB (0.39) | POLBSMPD1MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL8724364 | 0.87 | MAPT (0.47) | KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8067412 | 0.86 | XDH (0.43) | MAPTCYP3A4SMN1; SMN2TSHRMRGPRX4 | |
| SCHEMBL8077202 | 0.82 | XDH (0.41) | MRGPRX4 | |
| SCHEMBL8082110 | 0.82 | XDH (0.41) | MRGPRX4 | |
| SCHEMBL8081952 | 0.82 | XDH (0.41) | MRGPRX4 | |
| SCHEMBL8080501 | 0.82 | XDH (0.41) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5800733-A | Photo cross-linkable liquid crystal derivatives | ROLIC AG (CH) | 1998-09-01 | — | — | US | disclosed |