Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075506 | 0.93 | CSF1R (0.39) | THRBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8080550 | 0.89 | THRB (0.45) | THRBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8067412 | 0.89 | XDH (0.43) | THRBMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL8724338 | 0.88 | KDM4E (0.37) | MAPTSMN1; SMN2POLBSMPD1TSHR | |
| SCHEMBL8077328 | 0.88 | MAPT (0.44) | THRBMAPTNPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8729280 | 0.87 | TNFRSF1A (0.41) | MAPTNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL8723328 | 0.86 | MAPT (0.43) | MAPTRAB9ASMN1; SMN2SMPD1CYP3A4 | |
| SCHEMBL8077421 | 0.85 | SMN1; SMN2 (0.48) | THRBMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8081983 | 0.84 | XDH (0.41) | THRBXDH | |
| SCHEMBL8080501 | 0.84 | XDH (0.41) | THRBXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755918-B1 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | ROLIC AG (CH) | 2000-09-06 | — | — | EP | disclosed |
| US-5800733-A | Photo cross-linkable liquid crystal derivatives | ROLIC AG (CH) | 1998-09-01 | — | — | US | disclosed |
| EP-0755918-A2 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | Rolic AG (CH) | 1997-01-29 | — | — | EP | disclosed |