Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721301 | 0.88 | PTPN1 (0.43) | LMNATSHRPTPN1MGAMGAA | |
| SCHEMBL2179103 | 0.80 | APP (0.66) | LMNATSHRPTPN1MGAMGAA | |
| SCHEMBL8721286 | 0.79 | APP (0.51) | LMNATSHRPTPN1MGAMGAA | |
| SCHEMBL11523469 | 0.77 | APP (0.61) | LMNATSHRPTPN1MGAMGAA | |
| SCHEMBL14838409 | 0.75 | HSD17B1 (0.41) | LMNAPTPN1GAAPKMMAPT | |
| SCHEMBL6738366 | 0.75 | TSHR (0.76) | LMNATSHRMGAMGAASI | |
| SCHEMBL8722148 | 0.75 | CHRNB2 (0.41) | LMNAPTPN1MGAMGAASI | |
| SCHEMBL7919533 | 0.74 | HSD17B1 (0.54) | LMNATSHRPTPN1MGAMGAA | |
| SCHEMBL11392466 | 0.73 | TSHR (0.73) | LMNATSHRMGAMGAASI | |
| Iodide SCHEMBL30804629 | 0.73 | TSHR (0.73) | LMNATSHRMGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998000430-A1 | IMIDAZOL DERIVATIVES USEFUL AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-08 | — | — | WO | disclosed |