SCHEMBL5600749

SCHEMBL5600749

C1=C(n2cccc2)CCC1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5601494 0.93 LMNA (0.33) LMNAMAPT
SCHEMBL5603589 0.91 MAPK1 (0.32) LMNAMAPTMAPK1
SCHEMBL5602957 0.91 MAPK1 (0.32) LMNAMAPTMAPK1
SCHEMBL5602657 0.91 MAPK1 (0.32) LMNAMAPTMAPK1
SCHEMBL5601172 0.91 MAPK1 (0.32) LMNAMAPTMAPK1
SCHEMBL8724368 0.72 CYP11B2 (0.44) LMNAMAPT
SCHEMBL11814787 0.69 MAPT (0.44) LMNAMAPT
SCHEMBL497532 0.67 MAPT (0.38) LMNAMAPT
SCHEMBL2073935 0.66 CYP11B2 (0.42) LMNAMAPT
SCHEMBL29749307 0.65 MEN1 (0.35) MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
CN-109755647-A A kind of magnesium battery electrolyte 麻城市天力科技有限公司 2019-05-14 CN disclosed
CN-102224105-B Method for preparing ssz-26/33 zeolites using novel structure directing agents CHEVRON USA INC 2013-09-04 CN disclosed
CN-103086948-A Preparation method of (S,S,S)-2-azabicyclo[3,3,0]octane-3-carboxylic acid SHANGHAI PUYI CHEMICAL TECHNOLOGY CO LTD 2013-05-08 CN disclosed
CN-101827814-B Novel carbamoylglycine derivatives DSM IP ASSETS BV 2012-11-28 CN disclosed
CN-102224105-A Method for preparing ssz-26/33 zeolites using novel structure directing agents CHEVRON USA INC 2011-10-19 CN disclosed
CN-102197026-A Method for the synthesis of a ramipril intermediate DSM IP ASSETS BV 2011-09-21 CN disclosed
CN-102186812-A Methods for preparing fluoroalkyl arylsulfinyl compounds and fluorinated compounds thereto UBE INDUSTRIES 2011-09-14 CN disclosed
CN-101827814-A Novel carbamoylglycine derivatives DSM IP ASSETS BV 2010-09-08 CN disclosed
CN-101679295-A Novel 5-substituted hydantoins DSM IP ASSETS BV 2010-03-24 CN disclosed
CN-100379735-C 1,2,3,4,7, 8-hexahydro-6H- [1,4] diazepino [6,7, 1-IJ ] quinoline derivatives as antipsychotic and antiobesity agents WYETH CORP (US) 2008-04-09 CN disclosed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
CN-1955180-A 1,2,3,4,7,8-hexahydro-6H-[1,4]diazepino[6,7,1-IJ] quinoline derivatives as antipsychotic and antiobesity agents WYETH CORP (US) 2007-05-02 CN disclosed
CN-1256374-C Coupling system (white filler/diene elastomer) based on polysulphide alkoxysilane, enamine and guanidine derivative MICHELIN TECH S A (FR) 2006-05-17 CN disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed
CN-1662534-A 1,2,3,4,7, 8-hexahydro-6H- [1,4] diazepino [6,7, 1-IJ ] quinoline derivatives as antipsychotic and antiobesity agents WYETH CORP (US) 2005-08-31 CN disclosed
CN-1440409-A Polycyclic compounds as inhibitors of PARP, VEGFR2 and MLK3 enzymes and uses CEPHALON INC (US) 2003-09-03 CN disclosed
CN-1315983-A Coupling system (white filler/diene elastomer) based on polysulphide alkoxysilane, enamine and guanidine derivative MICHELIN RECH TECH (FR) 2001-10-03 CN disclosed
CN-1046935-C Phenylalkan derivative, preparation of same and seperation of optical isomer of same HISAMITSU PHARMACEUTICAL CO (JP) 1999-12-01 CN disclosed