Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 4/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376200 | 0.80 | CA1 (0.55) | ALDH1A1KDM4EL3MBTL1LMNAGAA | |
| Ammonia Solution, Strong SCHEMBL8724525 | 0.79 | CA1 (0.53) | ALDH1A1KDM4EL3MBTL1LMNAGAA | |
| SCHEMBL6952240 | 0.77 | TRPV4 (0.41) | ALDH1A1KDM4EL3MBTL1LMNAGAA | |
| SCHEMBL29401113 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EL3MBTL1LMNAGAA | |
| SCHEMBL7371669 | 0.77 | KDM4E (0.40) | ALDH1A1KDM4EL3MBTL1LMNAGAA | |
| Hydrochloric Acid SCHEMBL29291617 | 0.75 | KDM4E (0.39) | ALDH1A1KDM4EL3MBTL1LMNAGAA | |
| SCHEMBL17168934 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4EL3MBTL1HSD11B1CCR6 | |
| SCHEMBL1768833 | 0.73 | TPH1 (0.42) | ALDH1A1KDM4EL3MBTL1LMNAGAA | |
| SCHEMBL1768828 | 0.73 | TPH1 (0.42) | ALDH1A1KDM4EL3MBTL1LMNAGAA | |
| SCHEMBL21633890 | 0.73 | POLB (0.44) | ALDH1A1KDM4EL3MBTL1LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852195-A | Pyranone compounds useful to treat retroviral infections | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-22 | — | — | US | disclosed |