Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 3/20 | 0.33 |
| ▸ | FEN1 | P39748 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491762 | 0.78 | ERCC5 (0.45) | KMT2AERCC5FEN1SLC6A2SLC6A4 | |
| SCHEMBL8813179 | 0.77 | SLC6A4 (0.45) | KMT2AERCC5FEN1SLC6A2SLC6A4 | |
| SCHEMBL6746643 | 0.76 | ERCC5 (0.36) | KMT2AERCC5FEN1SLC6A2SLC6A4 | |
| SCHEMBL8724282 | 0.75 | KMT2A (0.33) | KMT2AHPGDHTTMEN1 | |
| SCHEMBL8815650 | 0.74 | MEN1 (0.33) | KMT2AERCC5FEN1P2RX7ATM | |
| SCHEMBL8815642 | 0.73 | HDAC1 (0.39) | KMT2AALDH1A1HTTMEN1MAPT | |
| SCHEMBL7574482 | 0.72 | HPGD (0.33) | KMT2AHPGDALDH1A1POLBP2RX7 | |
| SCHEMBL8818588 | 0.72 | HTT (0.31) | HTTNPSR1 | |
| SCHEMBL8443704 | 0.72 | ERCC5 (0.61) | KMT2AERCC5FEN1SLC6A2SLC6A4 | |
| SCHEMBL8389663 | 0.72 | SMN1; SMN2 (0.36) | KMT2AERCC5FEN1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625505-B1 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-10-28 | — | — | EP | disclosed |
| EP-0625505-A2 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |