Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8389663 | 0.85 | SMN1; SMN2 (0.36) | HPGDKMT2ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8489056 | 0.85 | CYP2D6 (0.33) | HPGDKMT2ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL6746643 | 0.84 | ERCC5 (0.36) | HPGDKMT2ASMN1; SMN2ALDH1A1P2RX7 | |
| SCHEMBL8494921 | 0.83 | SMN1; SMN2 (0.35) | HPGDKMT2ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8724282 | 0.82 | KMT2A (0.33) | HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL8754724 | 0.81 | ALDH1A1 (0.32) | KMT2AALDH1A1POLB | |
| SCHEMBL8725793 | 0.79 | KMT2A (0.34) | HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL8388765 | 0.78 | PDE4D (0.36) | HPGDKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8724610 | 0.77 | ERCC5 (0.38) | HPGDKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8726570 | 0.77 | GPR119 (0.34) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| US-5374606-A | Pre- and postemergence | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |