Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | FABP7 | O15540 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14353134 | 0.83 | BCHE (0.39) | ALDH1A1LMNACAPN1LGALS8 | |
| SCHEMBL22073048 | 0.79 | LGALS8 (0.45) | ALDH1A1ELANELMNACAPN1FABP7 | |
| SCHEMBL24603586 | 0.78 | ALDH1A1 (0.40) | ALDH1A1ELANELMNAFABP7FABP5 | |
| SCHEMBL2028686 | 0.78 | ALDH1A1 (0.40) | ALDH1A1ELANELMNAFABP7FABP5 | |
| SCHEMBL30838590 | 0.77 | ALDH1A1 (0.49) | ALDH1A1ELANELMNAFABP7FABP5 | |
| SCHEMBL17085402 | 0.75 | ALDH1A1 (0.41) | ALDH1A1ELANEFABP7FABP5LGALS8 | |
| SCHEMBL22108020 | 0.75 | LGALS8 (0.45) | ALDH1A1LMNAFABP7FABP5LGALS8 | |
| SCHEMBL22108027 | 0.75 | LGALS8 (0.45) | ALDH1A1LMNAFABP7FABP5LGALS8 | |
| SCHEMBL29477375 | 0.75 | LGALS8 (0.45) | ALDH1A1LMNAFABP7FABP5LGALS8 | |
| SCHEMBL10309796 | 0.74 | ALDH1A1 (0.39) | ALDH1A1ELANELMNAFABP7FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423747-B1 | Glycosyl-etoposide prodrugs, process for their preparation and their use in combination with functionalised tumour-specific enzyme conjugates | BEHRINGWERKE AG (DE) | 1998-07-22 | — | — | EP | disclosed |
| EP-0423747-A2 | Glycosyl-etoposide prodrugs, process for their preparation and their use in combination with functionalised tumour-specific enzyme conjugates | BEHRINGWERKE Aktiengesellschaft (DE) | 1991-04-24 | — | — | EP | disclosed |