Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8723459 | 0.98 | GCK (0.44) | GCKALDH1A1NPSR1POLBKMT2A | |
| SCHEMBL13200038 | 0.85 | GCK (0.38) | GCKALDH1A1NPSR1POLBKMT2A | |
| SCHEMBL2956715 | 0.85 | L3MBTL1 (0.40) | GCKALDH1A1NPSR1POLBKMT2A | |
| SCHEMBL15381506 | 0.84 | EHMT2 (0.45) | GCKALDH1A1NPSR1KMT2AHPGD | |
| SCHEMBL3531433 | 0.76 | GCK (0.52) | GCKALDH1A1NPSR1POLBKMT2A | |
| SCHEMBL10395383 | 0.75 | POLB (0.46) | GCKALDH1A1NPSR1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL10396008 | 0.74 | POLB (0.45) | GCKALDH1A1NPSR1POLBKMT2A | |
| SCHEMBL8938457 | 0.71 | LPO (0.48) | ALDH1A1NPSR1POLBKMT2AHPGD | |
| SCHEMBL4984369 | 0.69 | POLB (0.42) | GCKALDH1A1POLBKMT2ARAB9A | |
| SCHEMBL1330612 | 0.69 | LMNA (0.43) | GCKALDH1A1NPSR1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690846-B1 | HERBICIDAL HETEROCYCLIC-SUBSTITUTED PYRIDINES | SHELL INT RESEARCH (NL) | 1998-01-07 | — | — | EP | claimed |