Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 6/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28840780 | 0.84 | CREBBP (0.62) | CNR1CREBBPCDC25ATNFICMT | |
| SCHEMBL7861333 | 0.84 | CNR1 (0.67) | CNR1CREBBPTNFCNR2L3MBTL1 | |
| SCHEMBL8476741 | 0.80 | CNR1 (0.59) | CNR1CREBBPTNFCNR2LMNA | |
| SCHEMBL27556316 | 0.80 | CNR1 (0.65) | CNR1CREBBPTNFL3MBTL1LMNA | |
| SCHEMBL11386460 | 0.77 | CNR1 (0.59) | CNR1CREBBPCDC25ATNFICMT | |
| SCHEMBL8416334 | 0.76 | CDC25A (0.65) | CNR1CREBBPCDC25AICMTMCL1 | |
| Catechol SCHEMBL27414690 | 0.76 | CREBBP (0.78) | CNR1CREBBPTNFL3MBTL1LMNA | |
| SCHEMBL7934794 | 0.76 | CNR1 (0.63) | CNR1CREBBPCNR2L3MBTL1LMNA | |
| SCHEMBL8118248 | 0.76 | CNR2 (0.54) | CNR1TNFCNR2LMNA | |
| SCHEMBL11381706 | 0.75 | HTR6 (0.57) | CNR1CREBBPTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767139-A | SKIN DISORDERS; ALOPECIA; PROSTATE CANCER | PFIZER, INC. (US) | 1998-06-16 | — | — | US | disclosed |
| EP-0628040-B1 | INDOLE DERIVATIVES AS STEROID 5 ALPHA-REDUCTASE INHIBITORS | PFIZER LTD (GB) | 1998-03-25 | — | — | EP | disclosed |
| EP-0628040-A1 | INDOLE DERIVATIVES AS STEROID 5 ALPHA-REDUCTASE INHIBITORS | Pfizer Limited (GB) | 1994-12-14 | — | — | EP | disclosed |
| WO-1993017014-A1 | INDOLE DERIVATIVES AS STEROID 5 ALPHA-REDUCTASE INHIBITORS | PFIZER LIMITED (GB) | 1993-09-02 | — | — | WO | disclosed |