SCHEMBL8724979

SCHEMBL8724979

NC(=O)c1ccc2c(c1C(N)=O)-c1cccc-2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.42
BTK Q06187 3/20 0.40
PLA2G2A P14555 8/20 0.40
PLA2G10 O15496 7/20 0.40
IKBKB O14920 4/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
PLA2G1B P04054 1/20 0.36
PLA2G5 P39877 1/20 0.36
PLA2G2C Q5R387 1/20 0.36
PLA2G12B Q9BX93 1/20 0.36
PLA2G12A Q9BZM1 1/20 0.36
PLA2G2F Q9BZM2 1/20 0.36
PLA2G3 Q9NZ20 1/20 0.36
PLA2G2E Q9NZK7 1/20 0.36
PLA2G2D Q9UNK4 1/20 0.36
DHODH Q02127 1/20 0.36
MKNK1 Q9BUB5 1/20 0.36
MKNK2 Q9HBH9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28029528 0.91 MAP4K4 (0.43) BCAT2BTKPLA2G2APLA2G10IKBKB
SCHEMBL4152514 0.84 BCAT2 (0.56) BCAT2PLA2G2APLA2G10IKBKBKEAP1
SCHEMBL10483681 0.82 BRD4 (0.39) BCAT2BTKPLA2G2APLA2G10IKBKB
SCHEMBL31194394 0.80 BCAT2 (0.55) BCAT2PLA2G2APLA2G10IKBKBKEAP1
SCHEMBL29374101 0.79 IKBKB (0.47) BCAT2PLA2G2APLA2G10IKBKBKEAP1
SCHEMBL169868 0.79 IKBKB (0.47) BCAT2PLA2G2APLA2G10IKBKBKEAP1
SCHEMBL28268781 0.79 BCAT2 (0.44) BCAT2BTKPLA2G2APLA2G10IKBKB
SCHEMBL18045544 0.78 MAP4K4 (0.43) BCAT2BTKPLA2G2APLA2G10IKBKB
SCHEMBL28790248 0.76 TLR8 (0.45) BTKDHODH
SCHEMBL28029850 0.76 BCAT2 (0.38) BCAT2BTKIKBKBMKNK1MKNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5702610-A PASSING FLUID CONTAINING ANALYTE THROUGH SOLID PHASE EXTRACTION OR REACTION SHEET COMPRISING SORPTIVE POLYMER PULP HAVING PARTICLES ENMESHED THEREIN, WHEREIN ANALYTE BECOMES BOUND TO PULP OR PARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-12-30 US claimed
US-5688370-A ABSORPTIVE POLYMER PULP MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-11-18 US claimed
EP-0735920-B1 USE OF SHEET MATERIALS FOR SOLID PHASE EXTRACTIONS AND SOLID PHASE REACTIONS MINNESOTA MINING & MFG (US) 1998-08-05 EP disclosed
US-5702610-A PASSING FLUID CONTAINING ANALYTE THROUGH SOLID PHASE EXTRACTION OR REACTION SHEET COMPRISING SORPTIVE POLYMER PULP HAVING PARTICLES ENMESHED THEREIN, WHEREIN ANALYTE BECOMES BOUND TO PULP OR PARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-12-30 US disclosed
US-5688370-A ABSORPTIVE POLYMER PULP MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-11-18 US disclosed
EP-0735920-A1 USE OF SHEET MATERIALS FOR SOLID PHASE EXTRACTIONS AND SOLID PHASE REACTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-10-09 EP disclosed
WO-1995017247-A1 SHEET MATERIALS FOR SOLID PHASE EXTRACTIONS AND SOLID PHASE REACTIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-06-29 WO disclosed