SCHEMBL169868

SCHEMBL169868

NC(=O)c1ccc(C(N)=O)c2c1-c1cccc-2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 3/20 0.47
BCAT2 O15382 1/20 0.47
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
DHODH Q02127 1/20 0.43
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
GAA P10253 1/20 0.42
MKNK1 Q9BUB5 3/20 0.42
MKNK2 Q9HBH9 3/20 0.42
JAK2 O60674 2/20 0.42
SIRT2 Q8IXJ6 1/20 0.42
SIRT1 Q96EB6 1/20 0.42
JAK3 P52333 1/20 0.42
AURKA O14965 1/20 0.42
BRD4 O60885 1/20 0.42
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29374101 1.00 IKBKB (0.47) IKBKBBCAT2KEAP1NFE2L2DHODH
SCHEMBL8949874 0.92 DHODH (0.46) IKBKBBCAT2KEAP1NFE2L2DHODH
SCHEMBL27919911 0.88 MAP4K4 (0.50) IKBKBBCAT2KEAP1NFE2L2KDM4E
SCHEMBL7063111 0.88 PARP1 (0.52) IKBKBBCAT2ALDH1A1MKNK1MKNK2
SCHEMBL10701680 0.86 CHEK1 (0.47) IKBKBKDM4EALDH1A1GAAJAK2
SCHEMBL4151580 0.84 BCAT2 (0.59) IKBKBBCAT2KEAP1NFE2L2KDM4E
SCHEMBL29771871 0.84 IKBKB (0.49) IKBKBBCAT2KEAP1NFE2L2DHODH
SCHEMBL17292699 0.83 BRD4 (0.51) ALDH1A1MKNK1MKNK2JAK2AURKA
SCHEMBL30037561 0.83 KEAP1 (0.41) IKBKBBCAT2KEAP1NFE2L2DHODH
SCHEMBL8724979 0.79 BCAT2 (0.42) IKBKBBCAT2KEAP1NFE2L2DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11390757-B2 Coated spring ThyssenKrupp Federn und Stabilisatoren GmbH (DE) 2022-07-19 US claimed
US-9782741-B2 Method for conducting sonochemical reactions and processes ARISDYNE SYSTEMS, INC. (US) 2017-10-10 US claimed
US-20170189883-A1 METHOD FOR CONDUCTING SONOCHEMICAL REACTIONS AND PROCESSES ARISDYNE SYSTEMS, INC. 2017-07-06 US claimed
EP-3174708-A1 FURAN BASED POLYAMIDES AND ARTICLES MADE THEREFROM E. I. du Pont de Nemours and Company (US) 2017-06-07 EP claimed
EP-1932877-B1 MOLDED ARTICLE AND METHOD OF PRODUCING THE SAME TEIJIN ENG (JP) 2016-03-16 EP claimed
US-20130029398-A1 FORMED ARTICLE AND PROCESS FOR THE PRODUCTION THEREOF TEIJIN ENGINEERING LTD. (JP) 2013-01-31 US claimed
JP-2011514671-A 2011-05-06 JP claimed
US-20110046268-A1 Self-Filleting Die Attach Paste WANG MINGHAI 2011-02-24 US claimed
EP-2250227-A1 SELF-FILLETING DIE ATTACH PASTE Henkel AG & Co. KGaA (DE) 2010-11-17 EP claimed
US-20100130347-A1 FORMED ARTICLE AND PROCESS FOR THE PRODUCTION THEREOF TEIJIN ENGINEERING LTD. (JP) 2010-05-27 US claimed
EP-0735920-B1 USE OF SHEET MATERIALS FOR SOLID PHASE EXTRACTIONS AND SOLID PHASE REACTIONS MINNESOTA MINING & MFG (US) 1998-08-05 EP claimed
EP-0790860-A1 SOLID PHASE EXTRACTION USING COMPOSITE SHEET FOR DIRECT MEASUREMENT OF RADIOACTIVITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-08-27 EP claimed
US-5637506-A QUANTITATIVE AND QUALITATIVE ANALYSIS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-06-10 US claimed
WO-1996014931-A1 SOLID PHASE EXTRACTION USING COMPOSITE SHEET FOR DIRECT MEASUREMENT OF RADIOACTIVITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-05-23 WO claimed
US-4559782-A Turbocharger drain line with reinforced flexible conduit CUMMINS ENGINE COMPANY, INC. (US) 1985-12-24 US claimed
EP-0059867-B1 THIN INSULATING SHEET MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1985-09-11 EP claimed
EP-0059866-B1 THIN INSULATING SHEET MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1985-09-04 EP claimed
US-4536437-A MULTILAYER-POLYAMIDE AND CARBON BLACK BASE, AND INK LAYER CONTAINING RESIN RICOH COMPANY, LTD. (JP) 1985-08-20 US claimed
US-4399191-A POLYMER FILM MELT BONDED TO POLMER FIBRILS MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1983-08-16 US claimed
US-4399190-A POLYIMIDE, POLYAMIDE, POLYPARABANIC ACID OR POLYESTER FILMS IMPREGNATED AND MELT-BONDED TO POLYMER DIBRILS MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1983-08-16 US claimed