Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | IL6ST | P40189 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957774 | 1.00 | NAAA (0.35) | NAAAIL6STCRHBPCRHR2PPARA | |
| SCHEMBL6956827 | 0.87 | CRHBP (0.39) | NAAAIL6STCRHBPCRHR2PTPN1 | |
| SCHEMBL7945756 | 0.87 | CRHBP (0.39) | NAAAIL6STCRHBPCRHR2PTPN1 | |
| SCHEMBL6950257 | 0.87 | CRHBP (0.39) | NAAAIL6STCRHBPCRHR2PTPN1 | |
| SCHEMBL6950253 | 0.87 | CRHBP (0.39) | NAAAIL6STCRHBPCRHR2PTPN1 | |
| SCHEMBL6950922 | 0.87 | CRHBP (0.39) | NAAAIL6STCRHBPCRHR2PTPN1 | |
| SCHEMBL6956993 | 0.83 | CRHBP (0.32) | IL6STCRHBPCRHR2PTPN1 | |
| SCHEMBL6947001 | 0.81 | CRHBP (0.31) | NAAAIL6STCRHBPCRHR2 | |
| SCHEMBL8724413 | 0.79 | CRHBP (0.38) | NAAAIL6STCRHBPCRHR2PPARA | |
| SCHEMBL6954293 | 0.79 | AVPR1A (0.37) | NAAAIL6STCRHBPCRHR2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852195-A | Pyranone compounds useful to treat retroviral infections | PHARMACIA & UPJOHN COMPANY (US) | 1998-12-22 | — | — | US | disclosed |