Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 5/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725467 | 1.00 | HSD11B1 (0.41) | HSD11B1GRIA1GRIA2GRIA3FASN | |
| SCHEMBL8725472 | 1.00 | HSD11B1 (0.41) | HSD11B1GRIA1GRIA2GRIA3FASN | |
| SCHEMBL9475349 | 0.96 | HSD11B1 (0.43) | HSD11B1GRIA1GRIA2GRIA3FASN | |
| SCHEMBL9475342 | 0.96 | HSD11B1 (0.43) | HSD11B1GRIA1GRIA2GRIA3FASN | |
| SCHEMBL8725348 | 0.81 | SLC18A3 (0.37) | — | |
| SCHEMBL8725353 | 0.81 | SLC18A3 (0.37) | — | |
| SCHEMBL8725355 | 0.81 | SLC18A3 (0.37) | — | |
| SCHEMBL8730453 | 0.81 | SLC18A3 (0.51) | TSHRALDH1A1 | |
| SCHEMBL8730449 | 0.81 | SLC18A3 (0.51) | TSHRALDH1A1 | |
| SCHEMBL11617857 | 0.81 | GRIA1 (0.43) | HSD11B1GRIA1GRIA2GRIA3FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882695-A1 | BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY | CHISSO CORPORATION (JP) | 1998-12-09 | — | — | EP | disclosed |