Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13145256 | 0.93 | ESR1 (0.41) | EGFRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL328706 | 0.88 | ALOX5 (0.41) | EGFRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL10272267 | 0.88 | ALOX5 (0.41) | EGFRPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL28006185 | 0.87 | ESR1 (0.47) | ALOX5ESR1PTGS2 | |
| SCHEMBL13180438 | 0.87 | TDP1 (0.40) | EGFRALOX5ESR1FFAR1MAOA | |
| SCHEMBL29175219 | 0.87 | EGFR (0.42) | EGFRALOX5ESR1FFAR1MAOA | |
| SCHEMBL10272893 | 0.83 | EGFR (0.37) | EGFRALOX5ESR1FFAR1MAOA | |
| SCHEMBL328666 | 0.83 | EGFR (0.37) | EGFRALOX5ESR1FFAR1MAOA | |
| SCHEMBL328642 | 0.83 | EGFR (0.37) | EGFRALOX5ESR1FFAR1MAOA | |
| SCHEMBL872522 | 0.83 | EGFR (0.43) | EGFRALOX5FFAR1MAOAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143324-B2 | antioxidants with hindered phenol functionality perform better in curing of polybenzocyclobutene materials in air without undue degradation of key properties | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-03-27 | — | — | US | disclosed |
| US-7807757-B2 | stabilizing and at the same time phase compatibilizing plastics or plastic compositions by incorporating maleic anhydride or acrylic acid grafted copolymer or terpolymer (styrene/butadiene/styrene block copolymer grafted with maleic anhydride) obtained by reacting with a benzotriazole compound | CIBA SPECIALTY CHEMICALS CORP. (US) | 2010-10-05 | — | — | US | disclosed |
| US-20090275673-A1 | Benzocyclobutene based polymer formulations and methods for processing such formulations in oxidative environments | DOW GLOBAL TECHNOLOGIES LLC | 2009-11-05 | — | — | US | disclosed |
| EP-2042547-A1 | Benzocyclobutene based polymer formulations | Dow Global Technologies Inc. (US) | 2009-04-01 | — | — | EP | disclosed |
| US-20080051521-A1 | Functionalized polymers | PFAENDNER RUDOLF | 2008-02-28 | — | — | US | disclosed |