Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328706 | 1.00 | ALOX5 (0.41) | ALOX5PTGS2EGFRPSEN1PSEN2 | |
| SCHEMBL872574 | 0.88 | EGFR (0.40) | ALOX5PTGS2EGFRPSEN1PSEN2 | |
| SCHEMBL29175219 | 0.87 | EGFR (0.42) | ALOX5PTGS2EGFRTYRESR1 | |
| SCHEMBL13180438 | 0.87 | TDP1 (0.40) | ALOX5PTGS2EGFRTYRESR1 | |
| SCHEMBL28006185 | 0.84 | ESR1 (0.47) | ALOX5PTGS2ESR1 | |
| SCHEMBL1629294 | 0.83 | EGFR (0.41) | ALOX5PTGS2EGFRTYRMAOA | |
| SCHEMBL10272893 | 0.83 | EGFR (0.37) | ALOX5PTGS2EGFRTYRESR1 | |
| SCHEMBL328666 | 0.83 | EGFR (0.37) | ALOX5PTGS2EGFRTYRESR1 | |
| SCHEMBL328642 | 0.83 | EGFR (0.37) | ALOX5PTGS2EGFRTYRESR1 | |
| SCHEMBL872522 | 0.83 | EGFR (0.43) | ALOX5PTGS2EGFRTYRMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423298-A1 | Compressor oil composition | Nippon Oil Corporation (JP) | 2012-02-29 | — | — | EP | disclosed |