Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726981 | 0.92 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2CCR2CYP3A4 | |
| SCHEMBL8727353 | 0.87 | HSD11B1 (0.43) | SLC6A4SLC6A3SLC6A2HDAC3HDAC1 | |
| SCHEMBL8729811 | 0.80 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2MEN1KMT2A | |
| SCHEMBL8726233 | 0.80 | HSD11B1 (0.40) | SLC6A4SLC6A3SLC6A2MEN1KMT2A | |
| SCHEMBL8678297 | 0.74 | AKR1C3 (0.43) | CCR2CYP3A4AKR1B10AKR1C4AKR1C3 | |
| SCHEMBL10435375 | 0.74 | CYP1A2 (0.35) | CYP3A4MEN1KMT2ATSHRHSD11B1 | |
| SCHEMBL7507920 | 0.74 | AKR1C3 (0.44) | CYP3A4AKR1B10AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL6524970 | 0.73 | SLC6A4 (0.51) | SLC6A4SLC6A3SLC6A2OPRL1CYP2D6 | |
| SCHEMBL6524968 | 0.73 | SLC6A4 (0.51) | SLC6A4SLC6A3SLC6A2CYP3A4OPRL1 | |
| SCHEMBL8729401 | 0.73 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5833879-A | LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |