Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726233 | 0.92 | HSD11B1 (0.40) | HSD11B1KCNH2CACNA1ITRPA1SLC6A4 | |
| SCHEMBL8725824 | 0.87 | SLC6A4 (0.39) | HSD11B1SLC6A4SLC6A3SLC6A2MEN1 | |
| SCHEMBL8729811 | 0.85 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2MEN1KMT2A | |
| SCHEMBL8726981 | 0.80 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2MEN1KMT2A | |
| SCHEMBL8563389 | 0.79 | MEN1 (0.45) | HSD11B1KCNH2CACNA1IOPRM1MEN1 | |
| SCHEMBL8729401 | 0.78 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2MEN1KMT2A | |
| SCHEMBL10435375 | 0.77 | CYP1A2 (0.35) | HSD11B1KCNH2MEN1KMT2A | |
| SCHEMBL8435345 | 0.74 | OPRM1 (0.41) | HSD11B1KCNH2CACNA1IOPRM1SLC6A9 | |
| SCHEMBL4802446 | 0.74 | CYP1A2 (0.40) | HSD11B1OPRM1SLC6A9TRPA1SLC6A4 | |
| SCHEMBL4802440 | 0.74 | CYP1A2 (0.40) | HSD11B1OPRM1SLC6A9TRPA1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5833879-A | LOW TEMPERATURE MISCIBILITY AND COMPATIBILITY WITH OTHER LIQUID CRYSTAL COMPOUNDS; DISPLAYS CONTAINING MIXTURES OF AT LEAST TWO COMPOUNDS, PHYSICAL PROPERTIES | CHISSO CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |