Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655071 | 0.86 | NQO1 (0.44) | MAPTKMT2AKDM4EPOLBL3MBTL1 | |
| SCHEMBL8721612 | 0.83 | BRAF (0.38) | MAPTKMT2AKDM4EL3MBTL1HPGD | |
| SCHEMBL6440705 | 0.81 | RAB9A (0.55) | MAPTKMT2AKDM4EPOLBL3MBTL1 | |
| SCHEMBL8725379 | 0.78 | KDM4E (0.43) | MAPTKMT2AKDM4EPOLBL3MBTL1 | |
| SCHEMBL8725864 | 0.78 | NQO1 (0.54) | MAPTKMT2AKDM4EPOLBL3MBTL1 | |
| SCHEMBL8721609 | 0.77 | KMT2A (0.45) | MAPTKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL3440767 | 0.77 | MAPT (0.63) | MAPTKMT2AKDM4EPOLBL3MBTL1 | |
| SCHEMBL9479637 | 0.77 | MAPT (0.63) | MAPTKMT2AKDM4EPOLBL3MBTL1 | |
| SCHEMBL8725290 | 0.77 | POLB (0.41) | MAPTKDM4EPOLBL3MBTL1HPGD | |
| SCHEMBL9514574 | 0.76 | NQO1 (0.70) | MAPTKMT2AKDM4EPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040705-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR (US) | 1996-12-19 | — | — | WO | disclosed |