Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721647 | 0.79 | SMN1; SMN2 (0.49) | L3MBTL1TDP1MAPK1MAPTALDH1A1 | |
| SCHEMBL160177 | 0.73 | L3MBTL1 (0.46) | EGFRL3MBTL1TDP1CYP1A2CYP2D6 | |
| SCHEMBL8725869 | 0.72 | EGFR (0.44) | EGFRL3MBTL1TDP1CYP1A2CYP2D6 | |
| SCHEMBL5469903 | 0.69 | MEN1 (0.46) | EGFRMAPTALDH1A1LMNAHTT | |
| SCHEMBL5474830 | 0.69 | EGFR (0.49) | EGFRCYP1A2MAPTALDH1A1KMT2A | |
| SCHEMBL8725276 | 0.68 | BRAF (0.45) | EGFRL3MBTL1TDP1CYP1A2CYP2D6 | |
| SCHEMBL2778847 | 0.68 | ALDH1A1 (0.45) | L3MBTL1TDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL285182 | 0.68 | ALDH1A1 (0.45) | L3MBTL1TDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1301200 | 0.66 | ALDH1A1 (0.44) | L3MBTL1TDP1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7040556 | 0.66 | ALDH1A1 (0.44) | L3MBTL1TDP1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040705-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR (US) | 1996-12-19 | — | — | WO | disclosed |