Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721650 | 0.78 | MAPT (0.43) | LMNAHTTMAPTALDH1A1TDP1 | |
| SCHEMBL160145 | 0.72 | L3MBTL1 (0.46) | LMNAHTTMAPTALDH1A1TDP1 | |
| SCHEMBL8725866 | 0.72 | EGFR (0.48) | EGFRLMNAHTTMAPTALDH1A1 | |
| SCHEMBL127280 | 0.69 | ALDH1A1 (0.39) | MAPTALDH1A1NPSR1TDP1CYP1A2 | |
| SCHEMBL8725293 | 0.69 | IDO1 (0.42) | EGFRLMNAHTTMAPTALDH1A1 | |
| SCHEMBL161774 | 0.69 | L3MBTL1 (0.46) | LMNAHTTMAPTALDH1A1NPSR1 | |
| SCHEMBL10458094 | 0.68 | ALDH1A1 (0.38) | LMNAHTTMAPTALDH1A1NPSR1 | |
| SCHEMBL8970984 | 0.67 | MAPK10 (0.55) | LMNAHTTMAPTALDH1A1NPSR1 | |
| SCHEMBL25385566 | 0.66 | ALDH1A1 (0.33) | MAPTALDH1A1NPSR1TDP1CYP1A2 | |
| SCHEMBL11348720 | 0.66 | ALDH1A1 (0.68) | LMNAHTTMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040705-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR (US) | 1996-12-19 | — | — | WO | disclosed |