Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8723621 | 0.85 | NOS3 (0.44) | MAPTNOS3NOS1LMNAPOLB | |
| SCHEMBL8720598 | 0.83 | NOS3 (0.42) | MAPTNOS3NOS1POLB | |
| SCHEMBL8721916 | 0.81 | NOS3 (0.47) | MAPTNOS3NOS1KMT2AALDH1A1 | |
| SCHEMBL8721897 | 0.81 | NOS3 (0.43) | MAPTNOS3NOS1LMNA | |
| SCHEMBL8722143 | 0.79 | NOS3 (0.47) | MAPTNOS3NOS1 | |
| Hydrochloric Acid SCHEMBL8709283 | 0.79 | NOS3 (0.52) | MAPTNOS3NOS1LMNAPOLB | |
| SCHEMBL8386958 | 0.78 | NOS3 (0.42) | MAPTNOS3NOS1LMNAPOLB | |
| SCHEMBL7485164 | 0.78 | MAPT (0.50) | MAPTNOS3NOS1KMT2AWDR5 | |
| SCHEMBL8708647 | 0.78 | NOS3 (0.51) | MAPTNOS3NOS1ALDH1A1LMNA | |
| SCHEMBL8383543 | 0.77 | NOS3 (0.45) | MAPTNOS3NOS1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |