Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 6/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721916 | 0.92 | NOS3 (0.47) | NOS3NOS1HTR1ADRD2HTR2A | |
| SCHEMBL8383543 | 0.83 | NOS3 (0.45) | NOS3NOS1HTR1ADRD2HTR2A | |
| SCHEMBL8387078 | 0.82 | NOS3 (0.44) | NOS3NOS1HTR1ADRD2MAPT | |
| SCHEMBL8723621 | 0.81 | NOS3 (0.44) | NOS3NOS1MAPTSLC6A4 | |
| SCHEMBL8720598 | 0.79 | NOS3 (0.42) | NOS3NOS1HTR1ADRD2HTR2A | |
| SCHEMBL8725951 | 0.79 | MAPT (0.49) | NOS3NOS1MAPT | |
| SCHEMBL8724313 | 0.79 | HTR1F (0.41) | HTR1ADRD2MAPTSLC6A4 | |
| SCHEMBL8721897 | 0.79 | NOS3 (0.43) | NOS3NOS1HTR1ADRD2MAPT | |
| Phenylacetic Acid SCHEMBL8723973 | 0.79 | HTR1A (0.49) | NOS3NOS1HTR1ADRD2HTR2A | |
| SCHEMBL7483312 | 0.79 | NOS3 (0.49) | NOS3NOS1HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |