Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22020962 | 0.83 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2RECQLUSP2GAA | |
| SCHEMBL10080570 | 0.81 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2RECQLUSP2GAA | |
| SCHEMBL179555 | 0.78 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2RECQLUSP2GAA | |
| SCHEMBL8261443 | 0.78 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2RECQLUSP2GAA | |
| SCHEMBL10153213 | 0.76 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2RECQLUSP2GAA | |
| SCHEMBL4967922 | 0.76 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2RECQLUSP2GAA | |
| SCHEMBL28819145 | 0.76 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2RECQLUSP2GAA | |
| SCHEMBL17310700 | 0.74 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2RECQLUSP2GAA | |
| SCHEMBL862113 | 0.74 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2RECQLUSP2GAA | |
| SCHEMBL20623013 | 0.74 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2RECQLUSP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040318-A2 | COMPOSITIONS, METHODS AND KITS FOR DETECTING MELANOMA AND MARGINS OF MELANOMA | UNIVERSITY OF MIAMI (US) | 2012-03-29 | — | — | WO | claimed |
| WO-2012040318-A2 | COMPOSITIONS, METHODS AND KITS FOR DETECTING MELANOMA AND MARGINS OF MELANOMA | UNIVERSITY OF MIAMI (US) | 2012-03-29 | — | — | WO | disclosed |