Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17257995 | 0.98 | SMN1; SMN2 (0.40) | SMN1; SMN2KEAP1KDM4ESIGMAR1ALDH1A1 | |
| SCHEMBL12017298 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2KEAP1KDM4ESIGMAR1ALDH1A1 | |
| SCHEMBL28819145 | 0.82 | ALDH1A1 (0.44) | SMN1; SMN2KEAP1KDM4EALDH1A1RECQL | |
| SCHEMBL4967922 | 0.82 | ALDH1A1 (0.44) | SMN1; SMN2KEAP1KDM4EALDH1A1RECQL | |
| SCHEMBL522905 | 0.82 | ALOX15 (0.32) | ALOX15 | |
| SCHEMBL11640031 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2KEAP1KDM4ESIGMAR1ALDH1A1 | |
| SCHEMBL179555 | 0.80 | ALDH1A1 (0.41) | SMN1; SMN2KEAP1KDM4ESIGMAR1ALDH1A1 | |
| SCHEMBL10628686 | 0.79 | KDM4E (0.41) | SMN1; SMN2KEAP1KDM4EALDH1A1RECQL | |
| SCHEMBL31277000 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2KEAP1KDM4ESIGMAR1ALDH1A1 | |
| SCHEMBL10153213 | 0.78 | ALDH1A1 (0.40) | SMN1; SMN2KEAP1KDM4ESIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104768993-B | Method for preparing composite component | 科思创德国股份有限公司 | 2018-02-16 | — | — | CN | claimed |
| CN-103890059-B | Fiber strengthened poly-isocyanurate part and its manufacture method | 科思创德国股份有限公司 | 2017-07-18 | — | — | CN | claimed |
| US-20150252047-A1 | SUBSTITUTED INDAZOL-PYRROLOPYRIMIDINES USEFUL IN THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-09-10 | — | — | US | claimed |
| US-20150218173-A1 | SUBSTITUTED INDAZOL-PYRROLOPYRIMIDINES USEFUL IN THE TREATMENT OF HYPERFOLIFERATIVE DISORDERS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-08-06 | — | — | US | claimed |
| CN-104768993-A | Method for producing composite components | BAYER MATERIALSCIENCE AG | 2015-07-08 | — | — | CN | claimed |
| CN-103890059-A | FIBRE-REINFORCED POLYISOCYANURATE COMPONENT AND A METHOD FOR PRODUCTION THEREOF | BAYER IP GMBH | 2014-06-25 | — | — | CN | claimed |
| US-8431565-B2 | Substituted imidazoheterocycles | CARA THERAPEUTICS, INC. (US) | 2013-04-30 | — | — | US | claimed |
| US-20090149450-A1 | SUBSTITUTED IMIDAZOHETEROCYCLES | CARA THERAPEUTICS, INC. (US) | 2009-06-11 | — | — | US | claimed |
| EP-1797054-A2 | ARYL-AMINO SUBSTITUTED PYRROLOPYRIMIDINE MULTI-KINASE INHIBITING COMPOUNDS | OSI Pharmaceuticals, Inc. (US) | 2007-06-20 | — | — | EP | claimed |
| US-20070129364-A1 | Pyrrolopyridine kinase inhibiting compounds | OSI PHARMACEUTICALS, INC. | 2007-06-07 | — | — | US | claimed |
| US-20060211678-A1 | Aryl-amino substituted pyrrolopyrimidine multi-kinase inhibiting compounds | OSI PHARMACEUTICALS, INC. | 2006-09-21 | — | — | US | claimed |
| WO-2006017443-A2 | ARYL-AMINO SUBSTITUTED PYRROLOPYRIMIDINE MULTI-KINASE INHIBITING COMPOUNDS | OSI PHARMACEUTICALS, INC. (US) | 2006-02-16 | — | — | WO | claimed |
| EP-0678503-B1 | Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities | NOVARTIS AG (CH) | 1999-09-01 | — | — | EP | claimed |
| US-4429023-A | DIAMINE DISPERSANT OF PIGMENT IN BINDER | AKZONA INCORPORATED (US) | 1984-01-31 | — | — | US | claimed |
| US-4334887-A | DIAMINE COMPLEXING AGENT | AKZONA INCORPORATED (US) | 1982-06-15 | — | — | US | claimed |
| CN-119019346-A | Heterocyclic polyamine compound, preparation method and application thereof, and heterocyclic polyamine combined solution | 大连理工大学 | 2024-11-26 | — | — | CN | disclosed |
| US-11746091-B2 | Cannabinoid receptor modulators | ARENA PHARMACEUTICALS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |
| US-4429023-A | DIAMINE DISPERSANT OF PIGMENT IN BINDER | AKZONA INCORPORATED (US) | 1984-01-31 | — | — | US | disclosed |
| US-4334887-A | DIAMINE COMPLEXING AGENT | AKZONA INCORPORATED (US) | 1982-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149450-A1 | SUBSTITUTED IMIDAZOHETEROCYCLES | CNR1, CNR2, TRPV1 | SMN1; SMN2 3382/4885KEAP1 1294/4885KDM4E 3477/4885 |
| US-20060211678-A1 | Aryl-amino substituted pyrrolopyrimidine multi-kinase inhibiting compounds | BMX, ERBB2, FRK | SMN1; SMN2 1644/4885KEAP1 2052/4885KDM4E 975/4885 |
| US-11746091-B2 | Cannabinoid receptor modulators | CNR1, CNR2, TRPV1 | SMN1; SMN2 208/4885KEAP1 2753/4885KDM4E 3533/4885 |
| US-20070129364-A1 | Pyrrolopyridine kinase inhibiting compounds | BMX, ERBB2, FRK | SMN1; SMN2 1697/4885KEAP1 2327/4885KDM4E 1133/4885 |
| US-20150218173-A1 | SUBSTITUTED INDAZOL-PYRROLOPYRIMIDINES USEFUL IN THE TREATMENT OF HYPERFOLIFERATIVE DISORDERS | CCND2, ARG2, ARG1 | SMN1; SMN2 1733/4885KEAP1 1385/4885KDM4E 3846/4885 |
| US-20150252047-A1 | SUBSTITUTED INDAZOL-PYRROLOPYRIMIDINES USEFUL IN THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | CCND2, CCND1, CCNA1 | SMN1; SMN2 2350/4885KEAP1 2283/4885KDM4E 2277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.