Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.48 |
| ▸ | AR | P10275 | 6/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885022 | 0.82 | LMNA (0.58) | PGRARNR3C1ABCB11CYP3A4 | |
| SCHEMBL7887205 | 0.79 | PGR (0.61) | PGRARNR3C2NR3C1ABCB11 | |
| SCHEMBL13013558 | 0.69 | AR (0.73) | PGRARNR3C2 | |
| SCHEMBL7886106 | 0.68 | PGR (0.60) | PGRARNR3C2NR3C1ABCB11 | |
| SCHEMBL13474765 | 0.68 | PGR (0.66) | PGRARNR3C2NR3C1ABCB11 | |
| Gestonorone SCHEMBL17831151 | 0.67 | CYP3A4 (0.67) | PGRARNR3C2NR3C1ABCB11 | |
| Gestonorone SCHEMBL17831152 | 0.67 | CYP3A4 (0.67) | PGRARNR3C2NR3C1ABCB11 | |
| Gestonorone SCHEMBL20488186 | 0.67 | CYP3A4 (0.67) | PGRARNR3C2NR3C1ABCB11 | |
| Gestonorone SCHEMBL19834940 | 0.67 | CYP3A4 (0.67) | PGRARNR3C2NR3C1ABCB11 | |
| Gestonorone SCHEMBL141624 | 0.67 | CYP3A4 (0.67) | PGRARNR3C2NR3C1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886645-A1 | NEW 19-NOR-PREGNENE DERIVATIVES | LABORATOIRE THERAMEX (MC) | 1998-12-30 | — | — | EP | disclosed |
| WO-1997027210-A1 | NEW 19-NOR-PREGNENE DERIVATIVES | LABORATOIRE THERAMEX (MC) | 1997-07-31 | — | — | WO | disclosed |