Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | SHBG | P04278 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.55 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gestonorone SCHEMBL17831152 | 0.84 | CYP3A4 (0.67) | LMNACYP2C19NR3C1MAPTHIF1A | |
| Gestonorone SCHEMBL19834940 | 0.84 | CYP3A4 (0.67) | LMNACYP2C19NR3C1MAPTHIF1A | |
| Gestonorone SCHEMBL17831151 | 0.84 | CYP3A4 (0.67) | LMNACYP2C19NR3C1MAPTHIF1A | |
| Gestonorone SCHEMBL20488186 | 0.84 | CYP3A4 (0.67) | LMNACYP2C19NR3C1MAPTHIF1A | |
| Gestonorone SCHEMBL141624 | 0.84 | CYP3A4 (0.67) | LMNACYP2C19NR3C1MAPTHIF1A | |
| SCHEMBL7887205 | 0.83 | PGR (0.61) | LMNACYP2C19NR3C1MAPTHIF1A | |
| SCHEMBL8726203 | 0.82 | PGR (0.48) | LMNACYP2C19NR3C1MAPTHIF1A | |
| SCHEMBL7882963 | 0.79 | LMNA (0.62) | LMNACYP2C19NR3C1MAPTHIF1A | |
| SCHEMBL9472235 | 0.79 | LMNA (0.62) | LMNACYP2C19NR3C1MAPTHIF1A | |
| SCHEMBL7882960 | 0.76 | NR3C1 (0.69) | LMNACYP2C19NR3C1MAPTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180803-B1 | STEROID DRUGS | LABORATOIRE THERAMEX (MC) | 2001-01-30 | — | — | US | disclosed |
| EP-0886645-B1 | NEW 19-NOR-PREGNENE DERIVATIVES | THERAMEX (MC) | 1999-09-01 | — | — | EP | disclosed |
| EP-0886645-A1 | NEW 19-NOR-PREGNENE DERIVATIVES | LABORATOIRE THERAMEX (MC) | 1998-12-30 | — | — | EP | disclosed |
| WO-1997027210-A1 | NEW 19-NOR-PREGNENE DERIVATIVES | LABORATOIRE THERAMEX (MC) | 1997-07-31 | — | — | WO | disclosed |
| EP-0785212-A1 | New 19-nor-pregnene derivatives | LABORATOIRE THERAMEX (MC) | 1997-07-23 | — | — | EP | disclosed |